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Meg Ryan has posted a tribute to the departed filmmaker Rob Reiner, who was her director in the hit rom-com When Harry Met Sally.

A Devastating Incident

Reiner was located lifeless with his wife, Michele Singer Reiner, at their home in Los Angeles over the weekend.

“We will miss this man so deeply…” Ryan shared on Instagram, accompanying a photo of them together. “Our gratitude, Rob and Michele, for your faith in true love, stories, and joy. We appreciate your faith in human goodness and your deep patriotism.”

Court Case Developments

Reiner’s son Nick, 32, has been charged with two counts of first-degree murder and made a court appearance today. He’s being held without bail. It’s been reported that Reiner’s daughter Romy found her father’s body.

“I must hold onto hope that their tale doesn't conclude here, that awareness can be heightened from this,” Ryan continued. “Perhaps they would desire a legacy of hope and humanity, leading us toward empathy and tranquility.”

A Statement from Siblings

Reiner’s other children Jake and Romy released a message today. “No words can convey the constant, profound sorrow we feel,” they said. “The tragic, shattering loss of our parents is an experience no one should have to face. They were more than parents; they were our closest confidants.”

Colleagues and Friends Remember

Ryan’s co-star, Billy Crystal, joined in remembering Reiner with a statement shared yesterday alongside tributes from Larry David, Martin Short and Albert Brooks.

“No one matched his comic instinct, his dedication to rhythmic dialogue, or his elegant sharpening of drama,” the tribute noted. “For the actors, he loved them. For the writers he made them better. Freedom was his key offering. He listened to ideas and included you in the creative journey. Everyone felt like part of a crew. His direction was a gift, but his legacy is broader.”

An Enduring Filmography

When Harry Met Sally was a box office and critical triumph in 1989, earning over $93 million globally and securing Nora Ephron an Oscar nomination for best original screenplay.

Rob Reiner first encountered Michele Singer Reiner during the production of When Harry Met Sally. The pair were brought together by Barry Sonnenfeld, a fellow filmmaker and pal.

Reiner’s celebrated filmography also included classics such as Misery, Stand by Me and The Princess Bride. The director and his wife were married for 36 years.